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"RELMa-expressing macrophages protect against fatal lung damage and reduce parasite burden during helminth infection" ÀÔ´Ï´Ù.

ÀÌ ³í¹®¿¡¼­´Â ÈçÈ÷ M2 typeÀ̶ó°í ºÒ¸®´Â alternatively activated macrophage(AAM) type¿¡ Æ÷Ä¿½º¸¦ ¸ÂÃß¾ú½À´Ï´Ù.
±×Áß¿¡¼­µµ resistin-like molecule(RELMa)ÀÇ ¹ßÇöÀÌ macrophageÀÇ ¿ªÇÒ¿¡ ¾î¶°ÇÑ ¿µÇâÀ» ¹ÌÄ¡´ÂÁö ¾Ë¾Æº¸°íÀÚ ÇÏ¿´À¸¸ç,
°á°úÀûÀ¸·Î RELMa-expressing macrophage´Â helminth infection »óȲ¿¡¼­ lung damage¸¦ ¿ÏÈ­½ÃÅ°´Âµ¥ Áß¿äÇÑ ¿ªÇÒÀ» ÇÔÀ» È®ÀÎÇÏ¿´½À´Ï´Ù.

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- Lung macrophage¿¡ ´ëÇØ °øºÎÇÏ°íÀÚ
- macrophage¿¡¼­ RELMa ¹ßÇöÀÌ inflammation °¨¼Ò ¹× wound healingÀ» Áõ°¡½ÃÅ°´Â Ãø¸éÀ» º¼¶§, Á¦°¡ ÁøÇàÇϴ ½ÇÇè¿¡µµ ÀÌ maker¸¦ ÀÌ¿ëÇϸé ÁÁÀ» °Í °°´Ù´Â »ý°¢À» ÇÏ¿´½À´Ï´Ù.
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³í¹®¸µÅ©: https://immunology.sciencemag.org/content/4/35/eaau3814
 
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¾È³çÇϼ¼¿ä, ¼öÁöÀÔ´Ï´Ù. À̹ø ÁÖ Á¦°¡ ¹ßÇ¥ÇÒ ³í¹®Àº¿ÃÇØMucosal Immunology¿¡ °ÔÀçµÈ °ÍÀ¸·Î, Á¦¸ñÀº 'Regulatory T cells control the dynamic and site-specific polarization of total CD4 T cells following Salmonella infection.'ÀÔ´Ï´Ù. inflammation °ú mucosal homeostasis¸¦ Á¶ÀýÇÑ´Ù°í ¾Ë·ÁÁøT..