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2020-02-26
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Greetings, 

This is Heesang Hong. 

I am making this post to inform you that I will be presenting for this week's seminar (2/29).

The paper I have selected is 

"L-selectin Is Essential for Delivery of Activated CD8+ T Cells to Virus-Infected Organs for Protective Immunity".

It was published on Cell Reports, in 2016. 

The role L-selectin plays in the homing of activated CD8+ T cells to virus-infected organs has been much debated due to the cyclic nature of L-selectin expression by activated CD8+ T cells.

This paper suggests that L-selectin, in fact, plays a crucial role. Findings which back up this suggestion are presented clearly within the paper. 

Furthermore, it is proposed that the level of cell-surface L-selectin may determine the extent of anti-viral immunity. 

With possible applications, such as in the field of adoptive cell therapy for tumor treatment, I believe the findings from this paper surely are interesting.

Please check out the link below to download the full paper.
https://www.sciencedirect.com/science/article/pii/S2211124715015466

Thank you for your time, and I look forward to see you this Saturday. 

Best regards,

Heesang Hong.


 
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