¹Ù·Î°¡±â ¸Þ´º

¹Ù·Î°¡±â ¸Þ´º º»¹®³»¿ë ¹Ù·Î°¡±â ¸ÞÀθ޴º ¹Ù·Î°¡±â

ÁÖ¿ä¾È³»

HOME »çÀÌÆ®¸Ê

FONT SIZE

ÆùƮũ±â Å°¿ò 100% 110% 120% 130% 140% ÆùƮũ±â ÁÙÀÓ
¸Þ´ºº¸±â
 
Á¦¸ñ
2/8 ¹ßÇ¥³í¹® ÀÔ´Ï´Ù
ÀÛ¼ºÀÏ
2020-02-06
Á¶È¸¼ö
340


¾È³çÇϼ¼¿ä, À̹øÁÖ ¹ßÇ¥ÀÚ ¿µÁø ÀÔ´Ï´Ù.

 

Á¦°¡ ¼±Á¤ÇÑ ³í¹®Àº 2018³âµµ JEM¿¡ ÃâÆÇ µÈ

"Growth of Mycobacterium tuberculosis in vivo segregates with host macrophage metabolism and ontogeny" ÀÔ´Ï´Ù.


ÀÌ ³í¹®¿¡¼­´Â Ãʱâ Mycobacterium tuberculosis infecton »óȲ½Ã
alveolar macrophage vs. interstitial macrophage ¸¦ ¿©·¯ Ãø¸é¿¡¼­ ºÐ¼®ÇÏ°í ÀÖÀ¸¸ç

bacterial infection reponse, metabolic state´Â macrophage lineage¿¡ µû¶ó ´Ù¸§À» È®ÀÎ ÇÏ¿´½À´Ï´Ù.

 

ÀÌ ³í¹®À» ¼±Á¤ÇÑ ÀÌÀ¯´Â

- Alveolar macrophage °øºÎ ¹× macrophage lineage¿¡ µû¸¥ metabolic state¸¦ ¾Ë¾Æº¸°íÀÚ

- ½ÇÇ轺Ŵ ¹× °¢Á¾ ½ÇÇè¹æ¹ýµéÀ» ÃßÈÄ Á¦ ½ÇÇè¿¡ Âü°íÇÏ°íÀÚ ¼±Á¤ÇÏ¿´½À´Ï´Ù.

 

¿­½ÉÈ÷ ÁغñÇÏ¿© Åä¿äÀÏ¿¡ ºË°Ú½À´Ï´Ù.

°¨»çÇÕ´Ï´Ù.

 

Æò¿µÁø ¿Ã¸²

¹ßÇ¥³í¹®¸µÅ©: https://rupress.org/jem/article/215/4/1135/42429/Growth-of-Mycobacterium-tuberculosis-in-vivo

÷ºÎÆÄÀÏ:
÷ºÎÆÄÀÏÀÌ ¾ø½À´Ï´Ù.
´ÙÀ½±Û
2/8 ¹ßÇ¥³í¹®ÀÔ´Ï´Ù.
/ ±èö±Õ
À̹ø¿¡ ¹ßÇ¥ÇÒ ³í¹®ÀÇ Á¦¸ñÀº Naringenin Enhances the Antitumor Effect of Therapeutic Vaccines by Promoting Antigen Cross-Presentation À̸ç Áö³­ÇØ 12¿ù¿¡ Jounal of immunology ¿¡ ÃâÆǵǾú½À´Ï´Ù. ½Ä¹° À¯·¡ÀÇ metaboliteÀÇ ÇÑ Á¾·ùÀÎ FlavonoidsÀÎ NaringeninÀ̶ó´Â ¹°ÁúÀÌ Ç׿øÀÇ cross-presentationÀ» Çâ»ó..
ÀÌÀü±Û
2/1 ¹ßÇ¥³í¹®ÀÔ´Ï´Ù.
/ ±è³ª·¡
¾È³çÇϼ¼¿ä ³ª·¡ÀÔ´Ï´Ù. À̹øÁÖ ¼¼¹Ì³ª ¹ßÇ¥³í¹® ¼±Á¤ÇÏ¿© ¾Ë·Áµå¸³´Ï´Ù. Á¦°¡ À̹øÁÖ ¹ßÇ¥µå¸± ³í¹®Àº 2016³â Cell reports¿¡ °ÔÀçµÈ "IL-4 induces metallothionein 3- and SLC30A4-dependent increase in intracellular Zn2+ that promotes pathogen persistence in macrophages"¶ó´Â Á¦¸ñÀÇ ³í¹®À¸·Î ..