This is Mingyu Jin.
I am making this post to inform you that I will be presenting this week’s seminar (4/16).
The paper I am going to present is “Dietary Manipulation of the Gut Microbiome in Inflammatory Bowel Disease Patients: Pilot Study”.
It was published on Mucosal Immunology in February 2022.
The etiology of inflammatory bowel disease (IBD) is thought to be linked to an inappropriate immune response to an altered or dysbiotic gut microbiome in genetically susceptible individuals. Dietary interventions represent an ideal strategy to revert gut dysbiosis in IBD patients as diet change is often more embraced by individuals than medication.
In this study, the IBD-AID has been designed to revert dysbiosis in patients with IBD, through increased consumption of prebiotics and probiotics foods, beneficial foods necessary for human nutrition, and avoidance of foods known to trigger intestinal symptoms and dysbiosis.
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The IBD-AID can favor bacteria commonly depleted in IBD patients which are key for maintaining immune tolerance and homeostasis in the gut via SCFA production.
Consumption of prebiotics, probiotics, and beneficial foods correlated with increased abundance of Clostridia and Bacteroides, commonly depleted in IBD cohorts.
Specific foods categorized as prebiotics or adverse foods are correlated to levels of cytokines in serum (i.e., GM-CSF, IL-6, IL-8, TNF-α) that play a central role in IBD pathogenesis.
With possible applications, such as in the field of nutritional and microbial status in mice with IBD. I believe the findings from this paper surely are interesting.
Please check out the link below to download the full paper.
https://doi.org/10.1080/19490976.2022.2046244
Best regards.
Mingyu Jin.