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Á¦°¡ À̹øÁÖ¿¡ ¹ßÇ¥ÇÏ°Ô µÈ ³í¹®Àº 2017³â the Journal of  Immunology ¿¡ ½Ç¸° 'IL-6 Regulates M2 Polarization and Local Proliferation of Adipose Tissue Macrophages in Obesity' ÀÔ´Ï´Ù. ÇØ´ç ³í¹®¿¡¼­´Â IL-6°¡ obesity »óȲ¿¡¼­ Th2 cytokineÀ¸·Î ÀÛ¿ëÇÏ¿© M2 polarization °ú local ATM proliferationÀ» stimulate ÇÏ´Â °ÍÀ» ¹àÇô ³Â½À´Ï´Ù.

±âº»ÀûÀÎ adipose tissue macrophageÀÇ property¿¡ ´ëÇØ °øºÎÇÑ ³»¿ë°ú ±âÁ¸ÀÇ M1(classically activated macrophages)/M2(alternatively activated macrophages) paradigm ÀÌ¿Ü¿¡ Á¦½ÃµÈ local proliferation ¿¡ ¿µÇâÀ» Áִ cytokine treatment¿¡ ´ëÇØ ¼Ò°³µå¸®°íÀÚ ÇÕ´Ï´Ù.

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http://www.jimmunol.org/content/jimmunol/198/7/2927.full.pdf

http://www.jimmunol.org/content/198/7/2927.abstract


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4/20 ¹ßÇ¥³í¹®ÀÔ´Ï´Ù
/ payam.kassani
Hello everyone, The selected paper for upcoming Saturday as paper meeting presentation is: ¡° Liver receptor homolog-1 (NR5a2) regulates CD95/Fas ligand tran Published: Cell Death and Disease (2017). Based on my previous presentation, the nuclear receptor LRH-1 (NR5A2) plays a crucial..
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¾È³çÇϼ¼¿ä, À±Ã¶ÀÔ´Ï´Ù.À̹øÁÖ Á¦°¡ ¹ßÇ¥ÇÒ ³í¹®Àº 2019³â immunity À̹øÈ£¿¡ ³ª¿Â ³í¹®À¸·ÎLoss of Neurological Disease HSAN-I-Associated Gene SPTLC2 Impairs CD8 T Cell Responses to Infection by Inhibiting T Cell Metabolic Fitness¶ó´Â Á¦¸ñÀ¸·ÎGuoliang Cui ±×·ì¿¡¼­ ³ª¿Ô½À´Ï´Ù.Hereditary sensory neurophat..